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Profhilo vs Dermal Fillers: What’s the Difference?

25th January 2026

A Clear Guide for Your Skin Care Journey

If you’re thinking about ways to refresh your skin’s appearance, you may have heard of both Profhilo and dermal fillers. These treatments are often mentioned together, but they serve different purposes. This friendly guide explains the difference between the two so you can better understand what might suit your goals — especially if you’re considering Profhilo in Chelsea.

What Are Profhilo and Dermal Fillers?

Understanding the basics helps you see how these options vary.

Profhilo

Profhilo is a type of injectable treatment containing a high concentration of hyaluronic acid — a substance naturally found in skin that helps attract and hold moisture. Rather than filling specific lines or hollows, Profhilo spreads under the skin to improve hydration, texture and overall quality. It encourages your skin’s natural processes and has been described as a bio remodelling approach rather than a volumising one.

Dermal Fillers

Dermal fillers also use hyaluronic acid, but are formulated differently. Their main purpose is to fill and support areas of the face or body that have lost volume or definition. They’re commonly used to soften deeper lines, restore fullness to cheeks, or add shape to lips.

Both treatments involve injections, but the way they work and the outcomes people often look for are distinct.

How They Work: A Simple Comparison

Here’s a quick look at the differences in how each treatment affects the skin.

Feature Profhilo Dermal Fillers
Primary purpose Improve skin quality and hydration Add volume and contour to specific areas
How it spreads Diffuses under the skin Placed in targeted locations
Main effect Encourages overall hydration, elasticity, and texture Reduces lines, restores volume
Typical areas treated Face, neck, hands, décolletage Cheeks, lips, jawline, under-eye hollows
Results timeline Gradual (weeks) Often immediate
Duration of effect Several months Varies by product and area

These differences mean that while both can enhance your appearance, they do so in different ways and achieve different kinds of results.

Profhilo — Focus on Skin Quality

Profhilo’s approach centres on improving the skin’s condition from within. It doesn’t aim to change your features dramatically, but instead helps your natural hydration and elasticity improve. Some of the changes people notice include:

  • Smoother, more hydrated skin.
  • Improved texture and brightness.
  • Reduced visibility of fine lines.
  • A refreshed appearance without adding volume.

Evidence from clinical studies has shown that treatments like Profhilo can lead to measurable improvements in skin elasticity and hydration over time, especially when administered in a planned series of sessions.

Dermal Fillers — Targeted Support for Volume and Shape

Dermal fillers are commonly chosen when people want to enhance specific features or address deeper lines that form as fat pads and soft tissues in the face change over time. They are often used for:

  • Plumping thinning lips.
  • Restoring lost cheek volume.
  • Smoothing nasolabial folds (nose to mouth lines).
  • Reducing under-eye hollows.
  • Contouring the jawline.

Unlike Profhilo, which spreads beneath the skin, dermal fillers are placed precisely where volume is needed. The effects are often visible immediately after treatment. Results typically last several months, though this can vary depending on the area and product used.

Results: Immediate vs Gradual

Many people notice differences soon after dermal filler treatment, because the product is placed specifically where volume is needed. Profhilo’s effects, on the other hand, develop gradually — usually over a few weeks — as improved hydration and collagen/elastin stimulation take effect.

This means that Profhilo may feel subtler at first, but can result in skin that feels more supple and refreshed overall.

Research suggests that Profhilo continued to show improvements in skin quality over time when part of a series of treatments.

Who Might Choose Which?

Deciding between Profhilo and dermal fillers often comes down to what you want to achieve with your skin. Neither option is universally right or wrong — it’s about matching treatment to your personal goals and concerns.

Profhilo May Appeal to You If:

  • You want overall hydration and texture improvement.
  • You prefer a more natural, radiant appearance.
  • You’re interested in skin quality rather than volume change.
  • You’re noticing early signs of loss of elasticity.

Dermal Fillers May Appeal to You If:

  • You want to add or restore volume in specific areas.
  • You notice deeper lines or sagging.
  • You’re looking for changes that are visible right away.
  • You want to shape or contour specific features.

Both options are widely used and can complement one another when appropriate. Some people choose combination approaches — for example, improving overall skin quality with Profhilo and refining specific features with dermal fillers.

Safety and Aftercare

Both Profhilo and dermal fillers are generally well tolerated when performed in clinical settings. Mild reactions such as redness, swelling or tiny bumps at injection sites may occur but usually resolve within a couple of days.

As with any injectable treatment, proper aftercare supports optimal healing:

  • Avoid strenuous exercise on the day of treatment.
  • Use SPF daily to protect your skin.
  • Keep the treated area clean.
  • Follow any specific advice from your practitioner.

If you have skin conditions, allergies or are pregnant or breastfeeding, a consultation can clarify whether treatment is appropriate for you.

What to Expect at a Consultation

Before choosing Profhilo or dermal fillers, a consultation helps you explore your concerns, medical history and skin goals. During this visit, practitioners will:

  • Discuss your desired outcomes.
  • Assess your skin and facial structure.
  • Explain how each treatment works.
  • Recommend an approach that fits your needs.

This personalised discussion gives you space to ask questions and set realistic expectations.

Should You Consider It?

Understanding the difference between Profhilo and dermal fillers helps you make more confident decisions about your skin care options. If you’re curious about how Profhilo could enhance hydration and skin quality, or whether dermal fillers might address areas of volume loss, a consultation can be a good first step.

At Sadaf Jaffari Clinic, practitioners focus on tailoring discussions to your goals so you can choose a path that feels right for you.

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