If you’re thinking about ways to refresh your skin’s appearance, you may have heard of both Profhilo and dermal fillers. These treatments are often mentioned together, but they serve different purposes. This friendly guide explains the difference between the two so you can better understand what might suit your goals — especially if you’re considering Profhilo in Chelsea.
Understanding the basics helps you see how these options vary.
Profhilo is a type of injectable treatment containing a high concentration of hyaluronic acid — a substance naturally found in skin that helps attract and hold moisture. Rather than filling specific lines or hollows, Profhilo spreads under the skin to improve hydration, texture and overall quality. It encourages your skin’s natural processes and has been described as a bio remodelling approach rather than a volumising one.
Dermal fillers also use hyaluronic acid, but are formulated differently. Their main purpose is to fill and support areas of the face or body that have lost volume or definition. They’re commonly used to soften deeper lines, restore fullness to cheeks, or add shape to lips.
Both treatments involve injections, but the way they work and the outcomes people often look for are distinct.
Here’s a quick look at the differences in how each treatment affects the skin.
| Feature | Profhilo | Dermal Fillers |
| Primary purpose | Improve skin quality and hydration | Add volume and contour to specific areas |
| How it spreads | Diffuses under the skin | Placed in targeted locations |
| Main effect | Encourages overall hydration, elasticity, and texture | Reduces lines, restores volume |
| Typical areas treated | Face, neck, hands, décolletage | Cheeks, lips, jawline, under-eye hollows |
| Results timeline | Gradual (weeks) | Often immediate |
| Duration of effect | Several months | Varies by product and area |
These differences mean that while both can enhance your appearance, they do so in different ways and achieve different kinds of results.
Profhilo’s approach centres on improving the skin’s condition from within. It doesn’t aim to change your features dramatically, but instead helps your natural hydration and elasticity improve. Some of the changes people notice include:
Evidence from clinical studies has shown that treatments like Profhilo can lead to measurable improvements in skin elasticity and hydration over time, especially when administered in a planned series of sessions.
Dermal fillers are commonly chosen when people want to enhance specific features or address deeper lines that form as fat pads and soft tissues in the face change over time. They are often used for:
Unlike Profhilo, which spreads beneath the skin, dermal fillers are placed precisely where volume is needed. The effects are often visible immediately after treatment. Results typically last several months, though this can vary depending on the area and product used.
Many people notice differences soon after dermal filler treatment, because the product is placed specifically where volume is needed. Profhilo’s effects, on the other hand, develop gradually — usually over a few weeks — as improved hydration and collagen/elastin stimulation take effect.
This means that Profhilo may feel subtler at first, but can result in skin that feels more supple and refreshed overall.
Research suggests that Profhilo continued to show improvements in skin quality over time when part of a series of treatments.
Deciding between Profhilo and dermal fillers often comes down to what you want to achieve with your skin. Neither option is universally right or wrong — it’s about matching treatment to your personal goals and concerns.
Profhilo May Appeal to You If:
Dermal Fillers May Appeal to You If:
Both options are widely used and can complement one another when appropriate. Some people choose combination approaches — for example, improving overall skin quality with Profhilo and refining specific features with dermal fillers.
Both Profhilo and dermal fillers are generally well tolerated when performed in clinical settings. Mild reactions such as redness, swelling or tiny bumps at injection sites may occur but usually resolve within a couple of days.
As with any injectable treatment, proper aftercare supports optimal healing:
If you have skin conditions, allergies or are pregnant or breastfeeding, a consultation can clarify whether treatment is appropriate for you.
Before choosing Profhilo or dermal fillers, a consultation helps you explore your concerns, medical history and skin goals. During this visit, practitioners will:
This personalised discussion gives you space to ask questions and set realistic expectations.
Understanding the difference between Profhilo and dermal fillers helps you make more confident decisions about your skin care options. If you’re curious about how Profhilo could enhance hydration and skin quality, or whether dermal fillers might address areas of volume loss, a consultation can be a good first step.
At Sadaf Jaffari Clinic, practitioners focus on tailoring discussions to your goals so you can choose a path that feels right for you.
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